Elderly warned to stop taking common cure all

Reuters

They concluded that among patients aged 75 or older, the overall risk of developing serious bleeding was 10 times higher - which the authors concluded was "at least as likely to be disabling or fatal" as another stroke.

To TCTMD, Gurbel noted that the estimated number needed to treat (NNT) to prevent one upper gastrointestinal bleeding event at 5 years was 23 for patients aged 75 to 84 years and 21 for patients 85 years and older. "But our new study gives us a much clearer understanding of the size of the increased risk and of the severity and consequences of bleeds", said Professor Peter Rothwell, the study's lead author.

While the stomach bleeds can be potentially prevented by taking stomach-protecting PPI pills, taking daily aspirin in older people after a stroke or heart attack is still essential, and stopping aspirin use suddenly could be unsafe, according to the BBC. They also warn that stopping aspirin suddenly (for those who have been taking it regularly) could have some complications.

Worryingly, this advice was based on trials involving younger patients for just two to four years. The study covered a time frame of 10 years and recorded 314 study subjects who were admitted to the hospital on the account of bleeding.

The people aged over 75 are at higher risk of stomach bleed but the risk can be prevented by taking PPIs along with aspirin. For patients aged under 65, the annual rate of life-threatening or fatal bleeds was less than 0.5 percent, but for patients aged 75-84, the rate rose to approximately 1.5 percent. But doctors have been reluctant to add another drug to an elderly person's typically long list of medications, and the practice of viewing aspirin-related bleeds as minor also means that the risks of bleeding aren't being addressed properly.

The chances that bleeding was disabling or fatal, while lower, increased in roughly the same amounts equally across the different age groups. The second effect of (the) study is its support for the need to use PPIs in patients on antiplatelet therapy aged 75 years or older or in patients with a history of gastrointestinal bleeds.

Church bus crashes near Atlanta, killing 1
Harnering was one of several on a bus carrying students on their way to the airport for a mission trip to Botswana. The National Transportation Safety Board said it was gathering information but hadn't yet chose to launch a team.

Because the majority of patients studied were taking low-dose aspirin, rather than more modern anti-platelet drugs such as clopidogrel or AstraZeneca's Brilinta, the study could not draw conclusions about combined drug use. A daily aspirin dose of 75 mg is usually prescribed in both the US and Europe to prevent heart attacks or strokes.

"The second outcome of (the) study is its support for the need to use PPIs in patients on anti-platelet therapy aged 75 years or older or in patients with a history of gastro-intestinal bleeds".

But experts say the risks needed to be evaluated. For the patients who are under 65, the hospital admissions due to the bleeding are 1.5 percent.

But "the new data should provide reassurance that the benefits of PPI use at older age outweigh the risks".

Those without a history of heart attack or stroke should avoid taking aspirin as they got older, he suggested.

"It is clear from the data presented that, in the over-75s, taking PPI along with aspirin was associated with a reduced likelihood of bleeding", said Tony Fox, a professor in the Pharmaceutical Medicine Group at King's College London.

Related news:

Hot News

Sony Unveils New 'Spider-Man' Game at E3 Expo
Jun 15, 2017 - 01:59
In a press statement, Sony Interactive Entertainment president and global CEO Andrew House thanked fans for supporting the PS4. Speaking with Indonesian website 'JagatPlay' , Yoshida-San was asked about PlayStation Experience and the Tokyo Game Show.

isis-killer-beheading-video-story-top Tim Farron quits as leader of Liberal Democrats
Jun 15, 2017 - 01:55
But the party failed to return nearer to their 2010 level of 57 seats, despite hoping to attract the support of pro-Remain voters. While questions about his faith were legitimate, he said they "distracted" from the party's election campaign.

isis-killer-beheading-video-story-top Lead the Android Rebellion in Detroit: Become Human
Jun 14, 2017 - 05:38
While the first trailer feels much more like Quantic's other game Heavy Rain the new one feels much more like Watch_Dogs . The trailer begins by following android Markus as he attempts to break into a store and free the robots stored inside.

E3 2017: Walmart Lists Mario + Rabbids Kingdom Battle Day One Edition
Jun 14, 2017 - 05:36
There is an exploration part of the Mario + Rabbids: Kingdom Battle that is similar to the standard 3D Mario game. Mario + Rabbids: Kingdom Battle is set for release on August 29th 2017.

isis-killer-beheading-video-story-top Not Even The Referee Noticed Joe Hart's Blunder vs Scotland
Jun 13, 2017 - 07:20
Alex Oxlade-Chamberlain had broken the deadlock after 70 minutes before two Leigh Griffiths free-kicks put the Scots on the brink of victory.

isis-killer-beheading-video-story-top Warriors' Green stays in Game 4 after technical foul fiasco
Jun 12, 2017 - 08:47
Green went 50 shades of outraged when he got his third-quarter tech but knew it was his first. No announcement was ever made correcting the error, not that Green was listening for one.

European Union presses Britain to get its act together for Brexit talks
Jun 11, 2017 - 09:09
After the election, the right-wing UK Independence Party, which helped drive Brexit , was left with no seats in Parliament. Instead of opting for a post-election shuffle, the Prime Minister retained key figures in her cabinet.

Luke Bryan opening Game 6 broadcast from honky-tonk roof
Jun 11, 2017 - 09:09
And so we head back to Nashville, where you know it's going to be nuts. "You're in the Cup final, this is what it's all about". Preliminary returns for the game, which saw the Penguins hammer the Predators 6-0, have it leading the night by most measures.

UAE seeking 'change of policy, not regime' in Qatar: Minister
Jun 11, 2017 - 09:08
Officials quoted by Reuters said talks were taking place with Iran, Turkey and others to secure supplies of food and water. Qatar just finished one of the stadiums for the tournament, though others have yet to be built.

isis-killer-beheading-video-story-top New smart speaker expected as Apple kicks off conference
Jun 11, 2017 - 09:07
It's powered by an A8 processor that Apple says helps it tap into the cloud and provide the best audio experience in your room. It has been tested by some Apple employees in their homes for upwards of a year, according to people familiar with the matter.

isis-killer-beheading-video-story-top Croatian President, Kazakh Speaker Condemn Tehran Terror Attacks
Jun 11, 2017 - 09:05
On Thursday, authorities said the assailants were Iranian nationals and they had arrested six suspects, including one woman, since the attacks.

Clinging on to her job, Britain's May appoints new ministers
Jun 11, 2017 - 09:03
In fact, the Conservatives swept the southern seats of Scotland formerly belonging to the SNP. The result was a hung Parliament , with no party big enough to form an overall majority.

isis-killer-beheading-video-story-top Holtmann to become Ohio State head coach
Jun 10, 2017 - 09:20
Like Matta, he a coach of the Bulldogs before being hired by the Buckeyes , so there is something in common with his predecessor. Steele has been an outstanding recruiter for XU; his IN ties helped the Muskeeters land All-America candidate Trevon Bluiett.

Comey Hearing Suggests Obstruction of Justice Investigation Is More Plausible
Jun 10, 2017 - 09:17
Evan Jenkins, R-W.Va., knocked committee members as grandstanding and stopped just short of calling Comey a liar. But Trump supporters can argue that the president's hand was strengthened by Thursday's "Super Bowl" hearing.

isis-killer-beheading-video-story-top European Central Bank keeps stimulus in place
Jun 09, 2017 - 08:56
This in turn has kept the euro in check this week and it was down 0.15 per cent against the dollar in morning trade in Europe. Draghi said risks to growth are now "broadly balanced" - a tweak from last time out when risks were "tilted to the downside".